Publications (last 5 years)
E.R. Nebet, C. Aprea, J. Zoodsma … L. P. Wollmuth.(2025) Conservation of human NMDA receptor subunits and disease variants in zebrafish. BMC Genomics. doi.org/10.1186/s12864-025-12274-6
C. Sha, T. Van Brunt, J. Kudria, … L. P. Wollmuth, E. Speer, H. Hsieh. A graded neonatal mouse model of necrotizing enterocolitis demonstrates that mild enterocolitis is sufficient to activate microglia and increase cerebral cytokine expression. PLOS. doi.org/10.1371/journal.pone.0323626
A.J. Napoli, S. Laderwager, … L. P. Wollmuth & H. Sirotkin (2024) Developmental loss of NMDA receptors results in supernumerary forebrain neurons through delayed maturation of transit-amplifying neuroblasts. Scientific Reports. doi.org/10.1038/s41598-024-53910-7
G. Moody, A. Musco, J. Bennett & L. P. Wollmuth (2023) An integrated approach to evaluate the functional effects of disease-associated NMDA receptor variants. Neuropharmacology. 10.1016/j.neuropharm.2023.109703
N. Certain, Q. Gan, J. Bennett, H. Hsieh & L. P. Wollmuth (2023) Differential regulation of tetramerization of the AMPA receptor glutamate–gated ion channel by auxiliary subunits. JBC. doi.org/10.1016/j.jbc.2023.105227
Amin, J. B., M. He, … & L. P. Wollmuth (2023) Two gates mediate NMDAR activity and are under subunit-specific regulation. Nature Comms. doi.org/10.1038/s41467-023-37260-y
J. Zoodsma, … L. P. Wollmuth & H. Sirotkin (2022) Mol Autism BMC. Disruption of grin2B, an ASD-associated gene, produces social deficits in zebrafish. doi.org/10.1186/s13229-022-00516-3.
D. Henry*, C. Joselevitch*, G. Matthews, & L. P. Wollmuth (2021) Expression and distribution of synaptotagmin family members in the zebrafish retina. JCN. doi.org/10.1002/cne.25238
M. He, and L. P. Wollmuth (2021) Hidden intermediate states of NMDAR in synapse dynamics. Biophysical Journal. DOI: 10.1016/j.bpj.2021.11.229
G. Moody, A. Musco, & L. P. Wollmuth (2021) Deriving the Ca2+ Integral as a Single Index of the Clinical Outcome of NMDA Receptor Disease‐Associated Variants FASEB Journal. doi.org/10.1096/fasebj.2021.35.S1.03170
Amin, J. B.*, A. Gochman*, M. He, N. Certain, and L. P. Wollmuth (2021) NMDA receptors require multiple pre-opening gating steps for efficient synaptic activity. Neuron. 109: 488-501. doi: 10.1016/ j.neuron.2020.11.009. (PMCID: PMC7864875). *Authors contributed equally.
Reviews (last 5 years)
M. He & L. P. Wollmuth (2023) Activation of excitatory glycine NMDA receptors: At the mercy of a whimsical GluN1 subunit. JGP. doi.org/10.1085/jgp.202313391
K. Hansen, L. P. Wollmuth, … S. F. Traynelis (2021) Structure, function and pharmacology of glutamate receptor ion channels. Pharmacol Reviews, 73:1469–1658
Wollmuth, L. P., K. Chan, and L Groc. (2021) Diverse and complex modes of action of anti-NMDA receptor autoantibodies. Neuropharmacology, 194:1-17.
Amin, J. B.*, G. Moody*, & L. P. Wollmuth (2021) From bedside-to-bench: What disease-associated variants are teaching us about the NMDA receptor. The Journal of Physiology. Invited review. 599(2):397-416. (PMCID: PMC7483363) *Authors contributed equally.